Oleanolic Acid Enhances Mesenchymal Stromal Cell Osteogenic Potential by Inhibition of Notch Signaling

Oleanolic acid (OA), a pentacyclic triterpenoid, has been shown to modulate multiple signaling pathways in a variety of cell linages. But the mechanisms underlying OA-mediated mesenchymal stromal cell (MSC) osteogenic differentiation are not known. In this study, we examined effects of OA on cell vi...

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Detalles Bibliográficos
Autores principales: Shu, Bing, Zhao, Yongjian, Wang, Yongjun, Wang, Guangxi, Shang, Xifu, Britt, Michael, Olmedo, Margaret, Chelly, Marjorie, Morandi, Massimo Max, Barton, Shane, Dong, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539294/
https://www.ncbi.nlm.nih.gov/pubmed/28765584
http://dx.doi.org/10.1038/s41598-017-07633-7

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