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Suppression of Transposable Elements in Leukemic Stem Cells

Genomic transposable elements (TEs) comprise nearly half of the human genome. The expression of TEs is considered potentially hazardous, as it can lead to insertional mutagenesis and genomic instability. However, recent studies have revealed that TEs are involved in immune-mediated cell clearance. H...

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Detalles Bibliográficos
Autores principales:	Colombo, Anthony R., Zubair, Asif, Thiagarajan, Devi, Nuzhdin, Sergey, Triche, Timothy J., Ramsingh, Giridharan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539300/ https://www.ncbi.nlm.nih.gov/pubmed/28765607 http://dx.doi.org/10.1038/s41598-017-07356-9

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