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Machine Learning-Assisted Network Inference Approach to Identify a New Class of Genes that Coordinate the Functionality of Cancer Networks

Emerging evidence indicates the existence of a new class of cancer genes that act as “signal linkers” coordinating oncogenic signals between mutated and differentially expressed genes. While frequently mutated oncogenes and differentially expressed genes, which we term Class I cancer genes, are read...

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Detalles Bibliográficos
Autores principales: Ghanat Bari, Mehrab, Ung, Choong Yong, Zhang, Cheng, Zhu, Shizhen, Li, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539301/
https://www.ncbi.nlm.nih.gov/pubmed/28765560
http://dx.doi.org/10.1038/s41598-017-07481-5