Impaired Fear Extinction Due to a Deficit in Ca(2+) Influx Through L-Type Voltage-Gated Ca(2+) Channels in Mice Deficient for Tenascin-C

Mice deficient in the extracellular matrix glycoprotein tenascin-C (TNC(−/−)) express a deficit in specific forms of hippocampal synaptic plasticity, which involve the L-type voltage-gated Ca(2+) channels (L-VGCCs). The mechanisms underlying this deficit and its functional implications for learning...

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Detalles Bibliográficos
Autores principales: Morellini, Fabio, Malyshev, Aleksey, Volgushev, Maxim, Chistiakova, Marina, Papashvili, Giorgi, Fellini, Laetitia, Kleene, Ralf, Schachner, Melitta, Dityatev, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539374/
https://www.ncbi.nlm.nih.gov/pubmed/28824389
http://dx.doi.org/10.3389/fnint.2017.00016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539374/
https://www.ncbi.nlm.nih.gov/pubmed/28824389
http://dx.doi.org/10.3389/fnint.2017.00016

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