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Role of Fatty Acid Kinase in Cellular Lipid Homeostasis and SaeRS-Dependent Virulence Factor Expression in Staphylococcus aureus

The SaeRS two-component system is a master activator of virulence factor transcription in Staphylococcus aureus, but the cellular factors that control its activity are unknown. Fatty acid (FA) kinase is a two-component enzyme system required for extracellular FA uptake and SaeRS activity. Here, we d...

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Detalles Bibliográficos
Autores principales: Ericson, Megan E., Subramanian, Chitra, Frank, Matthew W., Rock, Charles O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539427/
https://www.ncbi.nlm.nih.gov/pubmed/28765222
http://dx.doi.org/10.1128/mBio.00988-17