Regulation of human glioma cell apoptosis and invasion by miR-152-3p through targeting DNMT1 and regulating NF2: MiR-152-3p regulate glioma cell apoptosis and invasion

BACKGROUND: MiRNAs are involved in aberrant DNA methylation through regulation of DNA methyltransferases (DNMTs) in the pathogenesis and progression of glioblastomas (GBM). MiR-152-3p was down-expressed in human malignancies, and served as a tumor suppressor. Neurofibromatosis type 2 (NF2) was signi...

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Detalles Bibliográficos
Autores principales: Sun, Jin, Tian, Xinhua, Zhang, Junqing, Huang, Yanlin, Lin, Xiaoning, Chen, Luyue, Zhang, Shizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539621/
https://www.ncbi.nlm.nih.gov/pubmed/28764788
http://dx.doi.org/10.1186/s13046-017-0567-4

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