Cargando…
Low-Cost and Rapid Fabrication of Metallic Nanostructures for Sensitive Biosensors Using Hot-Embossing and Dielectric-Heating Nanoimprint Methods
We propose two approaches—hot-embossing and dielectric-heating nanoimprinting methods—for low-cost and rapid fabrication of periodic nanostructures. Each nanofabrication process for the imprinted plastic nanostructures is completed within several seconds without the use of release agents and epoxy....
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539740/ https://www.ncbi.nlm.nih.gov/pubmed/28671600 http://dx.doi.org/10.3390/s17071548 |
_version_ | 1783254539316494336 |
---|---|
author | Lee, Kuang-Li Wu, Tsung-Yeh Hsu, Hsuan-Yeh Yang, Sen-Yeu Wei, Pei-Kuen |
author_facet | Lee, Kuang-Li Wu, Tsung-Yeh Hsu, Hsuan-Yeh Yang, Sen-Yeu Wei, Pei-Kuen |
author_sort | Lee, Kuang-Li |
collection | PubMed |
description | We propose two approaches—hot-embossing and dielectric-heating nanoimprinting methods—for low-cost and rapid fabrication of periodic nanostructures. Each nanofabrication process for the imprinted plastic nanostructures is completed within several seconds without the use of release agents and epoxy. Low-cost, large-area, and highly sensitive aluminum nanostructures on A4 size plastic films are fabricated by evaporating aluminum film on hot-embossing nanostructures. The narrowest bandwidth of the Fano resonance is only 2.7 nm in the visible light region. The periodic aluminum nanostructure achieves a figure of merit of 150, and an intensity sensitivity of 29,345%/RIU (refractive index unit). The rapid fabrication is also achieved by using radio-frequency (RF) sensitive plastic films and a commercial RF welding machine. The dielectric-heating, using RF power, takes advantage of the rapid heating/cooling process and lower electric power consumption. The fabricated capped aluminum nanoslit array has a 5 nm Fano linewidth and 490.46 nm/RIU wavelength sensitivity. The biosensing capabilities of the metallic nanostructures are further verified by measuring antigen–antibody interactions using bovine serum albumin (BSA) and anti-BSA. These rapid and high-throughput fabrication methods can benefit low-cost, highly sensitive biosensors and other sensing applications. |
format | Online Article Text |
id | pubmed-5539740 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-55397402017-08-11 Low-Cost and Rapid Fabrication of Metallic Nanostructures for Sensitive Biosensors Using Hot-Embossing and Dielectric-Heating Nanoimprint Methods Lee, Kuang-Li Wu, Tsung-Yeh Hsu, Hsuan-Yeh Yang, Sen-Yeu Wei, Pei-Kuen Sensors (Basel) Article We propose two approaches—hot-embossing and dielectric-heating nanoimprinting methods—for low-cost and rapid fabrication of periodic nanostructures. Each nanofabrication process for the imprinted plastic nanostructures is completed within several seconds without the use of release agents and epoxy. Low-cost, large-area, and highly sensitive aluminum nanostructures on A4 size plastic films are fabricated by evaporating aluminum film on hot-embossing nanostructures. The narrowest bandwidth of the Fano resonance is only 2.7 nm in the visible light region. The periodic aluminum nanostructure achieves a figure of merit of 150, and an intensity sensitivity of 29,345%/RIU (refractive index unit). The rapid fabrication is also achieved by using radio-frequency (RF) sensitive plastic films and a commercial RF welding machine. The dielectric-heating, using RF power, takes advantage of the rapid heating/cooling process and lower electric power consumption. The fabricated capped aluminum nanoslit array has a 5 nm Fano linewidth and 490.46 nm/RIU wavelength sensitivity. The biosensing capabilities of the metallic nanostructures are further verified by measuring antigen–antibody interactions using bovine serum albumin (BSA) and anti-BSA. These rapid and high-throughput fabrication methods can benefit low-cost, highly sensitive biosensors and other sensing applications. MDPI 2017-07-02 /pmc/articles/PMC5539740/ /pubmed/28671600 http://dx.doi.org/10.3390/s17071548 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Lee, Kuang-Li Wu, Tsung-Yeh Hsu, Hsuan-Yeh Yang, Sen-Yeu Wei, Pei-Kuen Low-Cost and Rapid Fabrication of Metallic Nanostructures for Sensitive Biosensors Using Hot-Embossing and Dielectric-Heating Nanoimprint Methods |
title | Low-Cost and Rapid Fabrication of Metallic Nanostructures for Sensitive Biosensors Using Hot-Embossing and Dielectric-Heating Nanoimprint Methods |
title_full | Low-Cost and Rapid Fabrication of Metallic Nanostructures for Sensitive Biosensors Using Hot-Embossing and Dielectric-Heating Nanoimprint Methods |
title_fullStr | Low-Cost and Rapid Fabrication of Metallic Nanostructures for Sensitive Biosensors Using Hot-Embossing and Dielectric-Heating Nanoimprint Methods |
title_full_unstemmed | Low-Cost and Rapid Fabrication of Metallic Nanostructures for Sensitive Biosensors Using Hot-Embossing and Dielectric-Heating Nanoimprint Methods |
title_short | Low-Cost and Rapid Fabrication of Metallic Nanostructures for Sensitive Biosensors Using Hot-Embossing and Dielectric-Heating Nanoimprint Methods |
title_sort | low-cost and rapid fabrication of metallic nanostructures for sensitive biosensors using hot-embossing and dielectric-heating nanoimprint methods |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539740/ https://www.ncbi.nlm.nih.gov/pubmed/28671600 http://dx.doi.org/10.3390/s17071548 |
work_keys_str_mv | AT leekuangli lowcostandrapidfabricationofmetallicnanostructuresforsensitivebiosensorsusinghotembossinganddielectricheatingnanoimprintmethods AT wutsungyeh lowcostandrapidfabricationofmetallicnanostructuresforsensitivebiosensorsusinghotembossinganddielectricheatingnanoimprintmethods AT hsuhsuanyeh lowcostandrapidfabricationofmetallicnanostructuresforsensitivebiosensorsusinghotembossinganddielectricheatingnanoimprintmethods AT yangsenyeu lowcostandrapidfabricationofmetallicnanostructuresforsensitivebiosensorsusinghotembossinganddielectricheatingnanoimprintmethods AT weipeikuen lowcostandrapidfabricationofmetallicnanostructuresforsensitivebiosensorsusinghotembossinganddielectricheatingnanoimprintmethods |