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The case for well-conducted experiments to validate statistical protocols for 2D gels: different pre-processing = different lists of significant proteins

BACKGROUND: The proteomics literature has seen a proliferation of publications that seek to apply the rapidly improving technology of 2D gels to study various biological systems. However, there is a dearth of systematic studies that have investigated appropriate statistical approaches to analyse the...

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Detalles Bibliográficos
Autores principales: Meleth, Sreelatha, Deshane, Jessy, Kim, Helen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC553976/
https://www.ncbi.nlm.nih.gov/pubmed/15707480
http://dx.doi.org/10.1186/1472-6750-5-7