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Notch1 signaling induces epithelial-mesenchymal transition in lens epithelium cells during hypoxia

BACKGROUND: Posterior Capsular Opacification (PCO) is one of the most common complications of cataract surgery which can result in severe visual damage. Epithelial-Mesenchymal Transition (EMT) of lens epithelium cells (LEC) is the pathological basis of PCO. Recent research showed that hypoxia acted...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Xiao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539888/
https://www.ncbi.nlm.nih.gov/pubmed/28764685
http://dx.doi.org/10.1186/s12886-017-0532-1