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Decreased Serum Sirtuin-1 in COPD

BACKGROUND: The protein deacetylase sirtuin-1 (SIRT1) is an antiaging molecule that is decreased in the lung in patients with COPD. Recently, SIRT1 was reported to be detectable in serum, but serum SIRT1 (s120S) levels have not yet been reported in patients with COPD. METHODS: Serum SIRT1 protein of...

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Detalles Bibliográficos
Autores principales: Yanagisawa, Satoru, Papaioannou, Andriana I., Papaporfyriou, Anastasia, Baker, Jonathan R., Vuppusetty, Chaitanya, Loukides, Stelios, Barnes, Peter J., Ito, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Chest Physicians 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540026/
https://www.ncbi.nlm.nih.gov/pubmed/28506610
http://dx.doi.org/10.1016/j.chest.2017.05.004