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Predictors of haematocrit in lumbar fusion for lumbar disc herniation: a surgical assessment

BACKGROUND: Low haematocrit (Hct) is associated with a higher rate of post-operative complications, increased mortality, and additional medical costs following cardiac surgery. Predictors of post-operative Hct in lumbar fusion are unclear and may be beneficial in avoiding adverse surgical outcomes....

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Autores principales: Cai, Qingchun, Zeng, Sixiang, Zhi, Liqiang, Wu, Junlong, Ma, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540221/
https://www.ncbi.nlm.nih.gov/pubmed/28764694
http://dx.doi.org/10.1186/s12891-017-1655-5
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author Cai, Qingchun
Zeng, Sixiang
Zhi, Liqiang
Wu, Junlong
Ma, Wei
author_facet Cai, Qingchun
Zeng, Sixiang
Zhi, Liqiang
Wu, Junlong
Ma, Wei
author_sort Cai, Qingchun
collection PubMed
description BACKGROUND: Low haematocrit (Hct) is associated with a higher rate of post-operative complications, increased mortality, and additional medical costs following cardiac surgery. Predictors of post-operative Hct in lumbar fusion are unclear and may be beneficial in avoiding adverse surgical outcomes. METHODS: A total of 704 lumbar disc herniation patients (385 males, 319 females) who underwent primary lumbar fusion surgery were reviewed in this retrospective study. RESULTS: In the 687 patients who met the selection criteria, the pre-operative Hct was 41.23 ± 4.57%, the post-operative Hct was 32.61 ± 4.52%, the peri-operative Hct decline was 8.62 ± 4.07%, the estimated intra-operative blood loss was 586.76 ± 346.62 mL, and the post-operative drainage was 489.33 ± 274.32 mL. Pre-operative Hct, estimated blood volume, estimated intra-operative blood loss, post-operative drainage, allogeneic blood transfusion, and age showed significant correlations with post-operative Hct, and all factors were involved in the final multiple regression model. Patients who received intensive care had lower post-operative Hct values, and the length of post-operative hospital stay was negatively correlated with post-operative Hct. CONCLUSIONS: Dangerously low post-operative Hct is related to the length of ICU stay and post-operative hospital stay. Age, pre-operative Hct, intra-operative blood loss, post-operative drainage, and units of allogeneic blood transfusion are significant predictors of post-operative Hct and Hct decline. Hct variations during the operation make the calculation of total blood loss difficult.
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spelling pubmed-55402212017-08-03 Predictors of haematocrit in lumbar fusion for lumbar disc herniation: a surgical assessment Cai, Qingchun Zeng, Sixiang Zhi, Liqiang Wu, Junlong Ma, Wei BMC Musculoskelet Disord Research Article BACKGROUND: Low haematocrit (Hct) is associated with a higher rate of post-operative complications, increased mortality, and additional medical costs following cardiac surgery. Predictors of post-operative Hct in lumbar fusion are unclear and may be beneficial in avoiding adverse surgical outcomes. METHODS: A total of 704 lumbar disc herniation patients (385 males, 319 females) who underwent primary lumbar fusion surgery were reviewed in this retrospective study. RESULTS: In the 687 patients who met the selection criteria, the pre-operative Hct was 41.23 ± 4.57%, the post-operative Hct was 32.61 ± 4.52%, the peri-operative Hct decline was 8.62 ± 4.07%, the estimated intra-operative blood loss was 586.76 ± 346.62 mL, and the post-operative drainage was 489.33 ± 274.32 mL. Pre-operative Hct, estimated blood volume, estimated intra-operative blood loss, post-operative drainage, allogeneic blood transfusion, and age showed significant correlations with post-operative Hct, and all factors were involved in the final multiple regression model. Patients who received intensive care had lower post-operative Hct values, and the length of post-operative hospital stay was negatively correlated with post-operative Hct. CONCLUSIONS: Dangerously low post-operative Hct is related to the length of ICU stay and post-operative hospital stay. Age, pre-operative Hct, intra-operative blood loss, post-operative drainage, and units of allogeneic blood transfusion are significant predictors of post-operative Hct and Hct decline. Hct variations during the operation make the calculation of total blood loss difficult. BioMed Central 2017-08-01 /pmc/articles/PMC5540221/ /pubmed/28764694 http://dx.doi.org/10.1186/s12891-017-1655-5 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Cai, Qingchun
Zeng, Sixiang
Zhi, Liqiang
Wu, Junlong
Ma, Wei
Predictors of haematocrit in lumbar fusion for lumbar disc herniation: a surgical assessment
title Predictors of haematocrit in lumbar fusion for lumbar disc herniation: a surgical assessment
title_full Predictors of haematocrit in lumbar fusion for lumbar disc herniation: a surgical assessment
title_fullStr Predictors of haematocrit in lumbar fusion for lumbar disc herniation: a surgical assessment
title_full_unstemmed Predictors of haematocrit in lumbar fusion for lumbar disc herniation: a surgical assessment
title_short Predictors of haematocrit in lumbar fusion for lumbar disc herniation: a surgical assessment
title_sort predictors of haematocrit in lumbar fusion for lumbar disc herniation: a surgical assessment
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540221/
https://www.ncbi.nlm.nih.gov/pubmed/28764694
http://dx.doi.org/10.1186/s12891-017-1655-5
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