Inhibition of Rho Kinase Induces Antioxidative Molecules and Suppresses Reactive Oxidative Species in Trabecular Meshwork Cells

PURPOSE: To investigate the effect of rho kinase inhibitors on oxidative stress in trabecular meshwork (TM) cells. METHODS: TM cells were isolated from the eyes of cynomolgus monkeys. Y-27632 and menadione were used to inhibit rho kinase and induce production of reactive oxygen species (ROS), respec...

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Detalles Bibliográficos
Autores principales: Fujimoto, Tomokazu, Inoue, Toshihiro, Ohira, Saori, Awai-Kasaoka, Nanako, Kameda, Takanori, Inoue-Mochita, Miyuki, Tanihara, Hidenobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540245/
https://www.ncbi.nlm.nih.gov/pubmed/28804648
http://dx.doi.org/10.1155/2017/7598140

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