Progress towards a public chemogenomic set for protein kinases and a call for contributions

Protein kinases are highly tractable targets for drug discovery. However, the biological function and therapeutic potential of the majority of the 500+ human protein kinases remains unknown. We have developed physical and virtual collections of small molecule inhibitors, which we call chemogenomic s...

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Detalles Bibliográficos
Autores principales: Drewry, David H., Wells, Carrow I., Andrews, David M., Angell, Richard, Al-Ali, Hassan, Axtman, Alison D., Capuzzi, Stephen J., Elkins, Jonathan M., Ettmayer, Peter, Frederiksen, Mathias, Gileadi, Opher, Gray, Nathanael, Hooper, Alice, Knapp, Stefan, Laufer, Stefan, Luecking, Ulrich, Michaelides, Michael, Müller, Susanne, Muratov, Eugene, Denny, R. Aldrin, Saikatendu, Kumar S., Treiber, Daniel K., Zuercher, William J., Willson, Timothy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540273/
https://www.ncbi.nlm.nih.gov/pubmed/28767711
http://dx.doi.org/10.1371/journal.pone.0181585

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