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An interaction map of circulating metabolites, immune gene networks, and their genetic regulation

BACKGROUND: Immunometabolism plays a central role in many cardiometabolic diseases. However, a robust map of immune-related gene networks in circulating human cells, their interactions with metabolites, and their genetic control is still lacking. Here, we integrate blood transcriptomic, metabolomic,...

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Detalles Bibliográficos
Autores principales: Nath, Artika P., Ritchie, Scott C., Byars, Sean G., Fearnley, Liam G., Havulinna, Aki S., Joensuu, Anni, Kangas, Antti J., Soininen, Pasi, Wennerström, Annika, Milani, Lili, Metspalu, Andres, Männistö, Satu, Würtz, Peter, Kettunen, Johannes, Raitoharju, Emma, Kähönen, Mika, Juonala, Markus, Palotie, Aarno, Ala-Korpela, Mika, Ripatti, Samuli, Lehtimäki, Terho, Abraham, Gad, Raitakari, Olli, Salomaa, Veikko, Perola, Markus, Inouye, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540552/
https://www.ncbi.nlm.nih.gov/pubmed/28764798
http://dx.doi.org/10.1186/s13059-017-1279-y