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An interaction map of circulating metabolites, immune gene networks, and their genetic regulation
BACKGROUND: Immunometabolism plays a central role in many cardiometabolic diseases. However, a robust map of immune-related gene networks in circulating human cells, their interactions with metabolites, and their genetic control is still lacking. Here, we integrate blood transcriptomic, metabolomic,...
Autores principales: | Nath, Artika P., Ritchie, Scott C., Byars, Sean G., Fearnley, Liam G., Havulinna, Aki S., Joensuu, Anni, Kangas, Antti J., Soininen, Pasi, Wennerström, Annika, Milani, Lili, Metspalu, Andres, Männistö, Satu, Würtz, Peter, Kettunen, Johannes, Raitoharju, Emma, Kähönen, Mika, Juonala, Markus, Palotie, Aarno, Ala-Korpela, Mika, Ripatti, Samuli, Lehtimäki, Terho, Abraham, Gad, Raitakari, Olli, Salomaa, Veikko, Perola, Markus, Inouye, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540552/ https://www.ncbi.nlm.nih.gov/pubmed/28764798 http://dx.doi.org/10.1186/s13059-017-1279-y |
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