Mismatch repair deficient hematopoietic stem cells are preleukemic stem cells

Whereas transformation events in hematopoietic malignancies may occur at different developmental stages, the initial mutation originates in hematopoietic stem cells (HSCs), creating a preleukemic stem cell (PLSC). Subsequent mutations at either stem cell or progenitor cell levels transform the PLSC...

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Detalles Bibliográficos
Autores principales: Qing, Yulan, Gerson, Stanton L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540588/
https://www.ncbi.nlm.nih.gov/pubmed/28767666
http://dx.doi.org/10.1371/journal.pone.0182175

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