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Changes in lipid membranes may trigger amyloid toxicity in Alzheimer's disease

Amyloid-beta peptides (Aβ), implicated in Alzheimer’s disease (AD), interact with the cellular membrane and induce amyloid toxicity. The composition of cellular membranes changes in aging and AD. We designed multi-component lipid models to mimic healthy and diseased states of the neuronal membrane....

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Detalles Bibliográficos
Autores principales:	Drolle, Elizabeth, Negoda, Alexander, Hammond, Keely, Pavlov, Evgeny, Leonenko, Zoya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540602/ https://www.ncbi.nlm.nih.gov/pubmed/28767712 http://dx.doi.org/10.1371/journal.pone.0182194

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