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Effects of liver-stage clearance by Primaquine on gametocyte carriage of Plasmodium vivax and P. falciparum
BACKGROUND: Primaquine (PQ) is the only currently licensed antimalarial that prevents Plasmodium vivax (Pv) relapses. It also clears mature P. falciparum (Pf) gametocytes, thereby reducing post-treatment transmission. Randomized PQ treatment in a treatment-to-reinfection cohort in Papua New Guinean...
Autores principales: | Wampfler, Rahel, Hofmann, Natalie E., Karl, Stephan, Betuela, Inoni, Kinboro, Benson, Lorry, Lina, Silkey, Mariabeth, Robinson, Leanne J., Mueller, Ivo, Felger, Ingrid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540608/ https://www.ncbi.nlm.nih.gov/pubmed/28732068 http://dx.doi.org/10.1371/journal.pntd.0005753 |
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