Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques

The ability to control lentivirus replication may be determined, in part, by the extent to which individual viral proteins are targeted by the immune system. Consequently, defining the antigens that elicit the most protective immune responses may facilitate the design of effective HIV-1 vaccines. He...

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Detalles Bibliográficos
Autores principales: Martins, Mauricio A., Shin, Young C., Gonzalez-Nieto, Lucas, Domingues, Aline, Gutman, Martin J., Maxwell, Helen S., Castro, Iris, Magnani, Diogo M., Ricciardi, Michael, Pedreño-Lopez, Nuria, Bailey, Varian, Betancourt, Dillon, Altman, John D., Pauthner, Matthias, Burton, Dennis R., von Bredow, Benjamin, Evans, David T., Yuan, Maoli, Parks, Christopher L., Ejima, Keisuke, Allison, David B., Rakasz, Eva, Barber, Glen N., Capuano, Saverio, Lifson, Jeffrey D., Desrosiers, Ronald C., Watkins, David I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540612/
https://www.ncbi.nlm.nih.gov/pubmed/28732035
http://dx.doi.org/10.1371/journal.ppat.1006529

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