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Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015

An outbreak of Ebola virus disease (EVD) in Liberia began in March 2014 and ended in January 2016. Epidemiological information on the EVD cases was collected and managed nationally; however, collection and management of the data were challenging at the time because surveillance and reporting systems...

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Autores principales: Furuse, Yuki, Fallah, Mosoka, Oshitani, Hitoshi, Kituyi, Ling, Mahmoud, Nuha, Musa, Emmanuel, Gasasira, Alex, Nyenswah, Tolbert, Dahn, Bernice, Bawo, Luke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540615/
https://www.ncbi.nlm.nih.gov/pubmed/28732038
http://dx.doi.org/10.1371/journal.pntd.0005804
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author Furuse, Yuki
Fallah, Mosoka
Oshitani, Hitoshi
Kituyi, Ling
Mahmoud, Nuha
Musa, Emmanuel
Gasasira, Alex
Nyenswah, Tolbert
Dahn, Bernice
Bawo, Luke
author_facet Furuse, Yuki
Fallah, Mosoka
Oshitani, Hitoshi
Kituyi, Ling
Mahmoud, Nuha
Musa, Emmanuel
Gasasira, Alex
Nyenswah, Tolbert
Dahn, Bernice
Bawo, Luke
author_sort Furuse, Yuki
collection PubMed
description An outbreak of Ebola virus disease (EVD) in Liberia began in March 2014 and ended in January 2016. Epidemiological information on the EVD cases was collected and managed nationally; however, collection and management of the data were challenging at the time because surveillance and reporting systems malfunctioned during the outbreak. EVD diagnostic laboratories, however, were able to register basic demographic and clinical information of patients more systematically. Here we present data on 16,370 laboratory samples that were tested between April 4, 2014 and March 29, 2015. A total of 10,536 traceable individuals were identified, of whom 3,897 were confirmed cases (positive for Ebola virus RNA). There were significant differences in sex, age, and place of residence between confirmed and suspected cases that tested negative for Ebola virus RNA. Age (young children and the elderly) and place of residence (rural areas) were the risk factors for death due to the disease. The case fatality rate of confirmed cases decreased from 80% to 63% during the study period. These findings may help support future investigations and lead to a fuller understanding of the outbreak in Liberia.
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spelling pubmed-55406152017-08-12 Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015 Furuse, Yuki Fallah, Mosoka Oshitani, Hitoshi Kituyi, Ling Mahmoud, Nuha Musa, Emmanuel Gasasira, Alex Nyenswah, Tolbert Dahn, Bernice Bawo, Luke PLoS Negl Trop Dis Research Article An outbreak of Ebola virus disease (EVD) in Liberia began in March 2014 and ended in January 2016. Epidemiological information on the EVD cases was collected and managed nationally; however, collection and management of the data were challenging at the time because surveillance and reporting systems malfunctioned during the outbreak. EVD diagnostic laboratories, however, were able to register basic demographic and clinical information of patients more systematically. Here we present data on 16,370 laboratory samples that were tested between April 4, 2014 and March 29, 2015. A total of 10,536 traceable individuals were identified, of whom 3,897 were confirmed cases (positive for Ebola virus RNA). There were significant differences in sex, age, and place of residence between confirmed and suspected cases that tested negative for Ebola virus RNA. Age (young children and the elderly) and place of residence (rural areas) were the risk factors for death due to the disease. The case fatality rate of confirmed cases decreased from 80% to 63% during the study period. These findings may help support future investigations and lead to a fuller understanding of the outbreak in Liberia. Public Library of Science 2017-07-21 /pmc/articles/PMC5540615/ /pubmed/28732038 http://dx.doi.org/10.1371/journal.pntd.0005804 Text en © 2017 Furuse et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Furuse, Yuki
Fallah, Mosoka
Oshitani, Hitoshi
Kituyi, Ling
Mahmoud, Nuha
Musa, Emmanuel
Gasasira, Alex
Nyenswah, Tolbert
Dahn, Bernice
Bawo, Luke
Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015
title Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015
title_full Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015
title_fullStr Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015
title_full_unstemmed Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015
title_short Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015
title_sort analysis of patient data from laboratories during the ebola virus disease outbreak in liberia, april 2014 to march 2015
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540615/
https://www.ncbi.nlm.nih.gov/pubmed/28732038
http://dx.doi.org/10.1371/journal.pntd.0005804
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