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Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015
An outbreak of Ebola virus disease (EVD) in Liberia began in March 2014 and ended in January 2016. Epidemiological information on the EVD cases was collected and managed nationally; however, collection and management of the data were challenging at the time because surveillance and reporting systems...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540615/ https://www.ncbi.nlm.nih.gov/pubmed/28732038 http://dx.doi.org/10.1371/journal.pntd.0005804 |
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author | Furuse, Yuki Fallah, Mosoka Oshitani, Hitoshi Kituyi, Ling Mahmoud, Nuha Musa, Emmanuel Gasasira, Alex Nyenswah, Tolbert Dahn, Bernice Bawo, Luke |
author_facet | Furuse, Yuki Fallah, Mosoka Oshitani, Hitoshi Kituyi, Ling Mahmoud, Nuha Musa, Emmanuel Gasasira, Alex Nyenswah, Tolbert Dahn, Bernice Bawo, Luke |
author_sort | Furuse, Yuki |
collection | PubMed |
description | An outbreak of Ebola virus disease (EVD) in Liberia began in March 2014 and ended in January 2016. Epidemiological information on the EVD cases was collected and managed nationally; however, collection and management of the data were challenging at the time because surveillance and reporting systems malfunctioned during the outbreak. EVD diagnostic laboratories, however, were able to register basic demographic and clinical information of patients more systematically. Here we present data on 16,370 laboratory samples that were tested between April 4, 2014 and March 29, 2015. A total of 10,536 traceable individuals were identified, of whom 3,897 were confirmed cases (positive for Ebola virus RNA). There were significant differences in sex, age, and place of residence between confirmed and suspected cases that tested negative for Ebola virus RNA. Age (young children and the elderly) and place of residence (rural areas) were the risk factors for death due to the disease. The case fatality rate of confirmed cases decreased from 80% to 63% during the study period. These findings may help support future investigations and lead to a fuller understanding of the outbreak in Liberia. |
format | Online Article Text |
id | pubmed-5540615 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-55406152017-08-12 Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015 Furuse, Yuki Fallah, Mosoka Oshitani, Hitoshi Kituyi, Ling Mahmoud, Nuha Musa, Emmanuel Gasasira, Alex Nyenswah, Tolbert Dahn, Bernice Bawo, Luke PLoS Negl Trop Dis Research Article An outbreak of Ebola virus disease (EVD) in Liberia began in March 2014 and ended in January 2016. Epidemiological information on the EVD cases was collected and managed nationally; however, collection and management of the data were challenging at the time because surveillance and reporting systems malfunctioned during the outbreak. EVD diagnostic laboratories, however, were able to register basic demographic and clinical information of patients more systematically. Here we present data on 16,370 laboratory samples that were tested between April 4, 2014 and March 29, 2015. A total of 10,536 traceable individuals were identified, of whom 3,897 were confirmed cases (positive for Ebola virus RNA). There were significant differences in sex, age, and place of residence between confirmed and suspected cases that tested negative for Ebola virus RNA. Age (young children and the elderly) and place of residence (rural areas) were the risk factors for death due to the disease. The case fatality rate of confirmed cases decreased from 80% to 63% during the study period. These findings may help support future investigations and lead to a fuller understanding of the outbreak in Liberia. Public Library of Science 2017-07-21 /pmc/articles/PMC5540615/ /pubmed/28732038 http://dx.doi.org/10.1371/journal.pntd.0005804 Text en © 2017 Furuse et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Furuse, Yuki Fallah, Mosoka Oshitani, Hitoshi Kituyi, Ling Mahmoud, Nuha Musa, Emmanuel Gasasira, Alex Nyenswah, Tolbert Dahn, Bernice Bawo, Luke Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015 |
title | Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015 |
title_full | Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015 |
title_fullStr | Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015 |
title_full_unstemmed | Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015 |
title_short | Analysis of patient data from laboratories during the Ebola virus disease outbreak in Liberia, April 2014 to March 2015 |
title_sort | analysis of patient data from laboratories during the ebola virus disease outbreak in liberia, april 2014 to march 2015 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540615/ https://www.ncbi.nlm.nih.gov/pubmed/28732038 http://dx.doi.org/10.1371/journal.pntd.0005804 |
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