CD4 is expressed on a heterogeneous subset of hematopoietic progenitors, which persistently harbor CXCR4 and CCR5-tropic HIV proviral genomes in vivo

Latent HIV infection of long-lived cells is a barrier to viral clearance. Hematopoietic stem and progenitor cells are a heterogeneous population of cells, some of which are long-lived. CXCR4-tropic HIVs infect a broad range of HSPC subtypes, including hematopoietic stem cells, which are multi-potent...

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Detalles Bibliográficos
Autores principales: Sebastian, Nadia T., Zaikos, Thomas D., Terry, Valeri, Taschuk, Frances, McNamara, Lucy A., Onafuwa-Nuga, Adewunmi, Yucha, Ryan, Signer, Robert A. J., Riddell IV, James, Bixby, Dale, Markowitz, Norman, Morrison, Sean J., Collins, Kathleen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540617/
https://www.ncbi.nlm.nih.gov/pubmed/28732051
http://dx.doi.org/10.1371/journal.ppat.1006509

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