Correcting nucleotide-specific biases in high-throughput sequencing data

BACKGROUND: High-throughput sequence (HTS) data exhibit position-specific nucleotide biases that obscure the intended signal and reduce the effectiveness of these data for downstream analyses. These biases are particularly evident in HTS assays for identifying regulatory regions in DNA (DNase-seq, C...

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Detalles Bibliográficos
Autores principales: Wang, Jeremy R., Quach, Bryan, Furey, Terrence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540620/
https://www.ncbi.nlm.nih.gov/pubmed/28764645
http://dx.doi.org/10.1186/s12859-017-1766-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540620/
https://www.ncbi.nlm.nih.gov/pubmed/28764645
http://dx.doi.org/10.1186/s12859-017-1766-x

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