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Correcting nucleotide-specific biases in high-throughput sequencing data
BACKGROUND: High-throughput sequence (HTS) data exhibit position-specific nucleotide biases that obscure the intended signal and reduce the effectiveness of these data for downstream analyses. These biases are particularly evident in HTS assays for identifying regulatory regions in DNA (DNase-seq, C...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540620/ https://www.ncbi.nlm.nih.gov/pubmed/28764645 http://dx.doi.org/10.1186/s12859-017-1766-x |