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Programmed death-1 pathway blockade produces a synergistic antitumor effect: combined application in ovarian cancer

Programmed death-1 (PD-1) and its ligand are part of the immune checkpoint pathway that down-regulates effector T cells in immune response, thereby causing immune suppression. The PD-1/programmed death-ligand 1 (PD-L1) pathway can be blocked by antibodies to reverse tumor-mediated immunosuppression....

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Detalles Bibliográficos
Autores principales:	Zhu, Xinxin, Lang, Jinghe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology 2017
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540723/ https://www.ncbi.nlm.nih.gov/pubmed/28657225 http://dx.doi.org/10.3802/jgo.2017.28.e64

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