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Intercellular Genetic Interaction Between Irf6 and Twist1 during Craniofacial Development
Interferon Regulatory Factor 6 (IRF6) and TWIST1 are transcription factors necessary for craniofacial development. Human genetic studies showed that mutations in IRF6 lead to cleft lip and palate and mandibular abnormalities. In the mouse, we found that loss of Irf6 causes craniosynostosis and mandi...
Autores principales: | Fakhouri, Walid D., Metwalli, Kareem, Naji, Ali, Bakhiet, Sarah, Quispe-Salcedo, Angela, Nitschke, Larissa, Kousa, Youssef A., Schutte, Brian C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540929/ https://www.ncbi.nlm.nih.gov/pubmed/28769044 http://dx.doi.org/10.1038/s41598-017-06310-z |
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