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Intercellular Genetic Interaction Between Irf6 and Twist1 during Craniofacial Development

Interferon Regulatory Factor 6 (IRF6) and TWIST1 are transcription factors necessary for craniofacial development. Human genetic studies showed that mutations in IRF6 lead to cleft lip and palate and mandibular abnormalities. In the mouse, we found that loss of Irf6 causes craniosynostosis and mandi...

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Detalles Bibliográficos
Autores principales:	Fakhouri, Walid D., Metwalli, Kareem, Naji, Ali, Bakhiet, Sarah, Quispe-Salcedo, Angela, Nitschke, Larissa, Kousa, Youssef A., Schutte, Brian C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540929/ https://www.ncbi.nlm.nih.gov/pubmed/28769044 http://dx.doi.org/10.1038/s41598-017-06310-z

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