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miR-155 Regulates IL-10-Producing CD24(hi)CD27(+) B Cells and Impairs Their Function in Patients with Crohn’s Disease

Regulatory interleukin-10 (IL-10)-producing B cells (B10 cells) play a critical role in preventing and curing autoimmune diseases in experimental mouse models. However, the precise cellular and molecular mechanisms of action of B10 cells in humans, especially in patients with Crohn’s disease (CD), r...

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Detalles Bibliográficos
Autores principales: Zheng, Yingxia, Ge, Wensong, Ma, Yanhui, Xie, Guohua, Wang, Weiwei, Han, Li, Bian, Bingxian, Li, Li, Shen, Lisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540954/
https://www.ncbi.nlm.nih.gov/pubmed/28824639
http://dx.doi.org/10.3389/fimmu.2017.00914

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