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Preferential production of IgM-secreting hybridomas by immunization with DNA vaccines coding for Ebola virus glycoprotein: use of protein boosting for IgG-secreting hybridoma production
PURPOSE: The goal of this study was to investigate the utility of DNA vaccines encoding Ebola virus glycoprotein (GP) as a vaccine type for the production of GP-specific hybridomas and antibodies. MATERIALS AND METHODS: DNA vaccines were constructed to express Ebola virus GP. Mice were injected with...
Autores principales: | Lee, Si-Hyeong, Han, Baek-Sang, Choe, Jongseon, Sin, Jeong-Im |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Vaccine Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540962/ https://www.ncbi.nlm.nih.gov/pubmed/28775978 http://dx.doi.org/10.7774/cevr.2017.6.2.135 |
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