Connexin 43 is required for the maintenance of mitochondrial integrity in brown adipose tissue

We investigated the role of connexin 43 (Cx43) in maintaining the integrity of mitochondria in brown adipose tissue (BAT). The functional effects of Cx43 were evaluated using inducible, adipocyte-specific Cx43 knockout in mice (Gja1 (adipoq)KO) and by overexpression and knockdown of Cx43 in cultured...

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Detalles Bibliográficos
Autores principales: Kim, Sang-Nam, Kwon, Hyun-Jung, Im, Seo-Woo, Son, Yeon-Ho, Akindehin, Seun, Jung, Young-Suk, Lee, Se Jeong, Rhyu, Im Joo, Kim, Il Yong, Seong, Je-Kyoung, Lee, Jinu, Yoo, Hee-Chan, Granneman, James G., Lee, Yun-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540980/
https://www.ncbi.nlm.nih.gov/pubmed/28769076
http://dx.doi.org/10.1038/s41598-017-07658-y

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