Increased EphA4-ephexin1 signaling in the medial prefrontal cortex plays a role in depression-like phenotype

Accumulating evidence suggests a role of the ephrin receptor EphA4 and the downstream protein ephexin1 in synaptic plasticity, which is implicated in depression. We examined whether EphA4–ephexin1 signaling plays a role in the pathophysiology of depression, and the antidepressant-like effect of EphA...

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Detalles Bibliográficos
Autores principales: Zhang, Ji-chun, Yao, Wei, Qu, Youge, Nakamura, Mayumi, Dong, Chao, Yang, Chun, Ren, Qian, Ma, Min, Han, Mei, Shirayama, Yukihiko, Hayashi-Takagi, Akiko, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541046/
https://www.ncbi.nlm.nih.gov/pubmed/28769056
http://dx.doi.org/10.1038/s41598-017-07325-2

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