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The Enigmatic Role of C9ORF72 in Autophagy

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the loss of motor neurons resulting in a progressive and irreversible muscular paralysis. Advances in large-scale genetics and genomics have revealed intronic hexanucleotide repeat expansions in the gene...

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Detalles Bibliográficos
Autores principales:	Nassif, Melissa, Woehlbier, Ute, Manque, Patricio A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541066/ https://www.ncbi.nlm.nih.gov/pubmed/28824365 http://dx.doi.org/10.3389/fnins.2017.00442

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