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Self-management research of asthma and good drug use (SMARAGD study): a pilot trial

Background Community pharmacists play an important role in supporting patients for optimal drug use. Objective To assess the effectiveness of monitoring in asthma patients with inhaled corticosteroids (ICS) on disease control. Setting Asthma patients using ICS were invited from two intervention (IG)...

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Autores principales: Kuipers, Esther, Wensing, Michel, de Smet, Peter, Teichert, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541115/
https://www.ncbi.nlm.nih.gov/pubmed/28597176
http://dx.doi.org/10.1007/s11096-017-0495-6
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author Kuipers, Esther
Wensing, Michel
de Smet, Peter
Teichert, Martina
author_facet Kuipers, Esther
Wensing, Michel
de Smet, Peter
Teichert, Martina
author_sort Kuipers, Esther
collection PubMed
description Background Community pharmacists play an important role in supporting patients for optimal drug use. Objective To assess the effectiveness of monitoring in asthma patients with inhaled corticosteroids (ICS) on disease control. Setting Asthma patients using ICS were invited from two intervention (IG) and two control pharmacies (CG). Method Participating patients completed questionnaires at the study start and at 6-month follow-up, including the Control of Allergic Rhinitis and Asthma Test (CARAT) questionnaire. IG patients completed the CARAT questionnaire every 2 weeks and received counselling on disease management, ICS adherence, and inhalation technique when scores were suboptimal, deteriorating, or absent. For Turbuhaler users, additional electronic monitoring (EMI) was available, with daily alerts for ICS intake. Main outcome measure As the primary outcome, CARAT scores at follow-up were compared between IG and CG using linear regression. As secondary outcome, refill adherence was compared using logistic regression. Results From March to July 2015, we enrolled 39 IG and 41 CG patients. At follow-up, CARAT scores did not differ between IG and CG (−0.19; 95% confidence interval [CI], −2.57 to 2.20), neither did patient numbers with ICS adherence >80% (0.82; 95% CI, 0.28–2.37). Among EMI users, CARAT scores did not differ, but ICS adherence >80% showed a 4.52-fold increase (95% CI, 1.56–13.1) compared with EMI nonusers. Conclusion Among community-dwelling asthma patients, pharmacist monitoring did not affect CARAT scores, but EMI use showed improved ICS refill adherence.
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spelling pubmed-55411152017-08-17 Self-management research of asthma and good drug use (SMARAGD study): a pilot trial Kuipers, Esther Wensing, Michel de Smet, Peter Teichert, Martina Int J Clin Pharm Research Article Background Community pharmacists play an important role in supporting patients for optimal drug use. Objective To assess the effectiveness of monitoring in asthma patients with inhaled corticosteroids (ICS) on disease control. Setting Asthma patients using ICS were invited from two intervention (IG) and two control pharmacies (CG). Method Participating patients completed questionnaires at the study start and at 6-month follow-up, including the Control of Allergic Rhinitis and Asthma Test (CARAT) questionnaire. IG patients completed the CARAT questionnaire every 2 weeks and received counselling on disease management, ICS adherence, and inhalation technique when scores were suboptimal, deteriorating, or absent. For Turbuhaler users, additional electronic monitoring (EMI) was available, with daily alerts for ICS intake. Main outcome measure As the primary outcome, CARAT scores at follow-up were compared between IG and CG using linear regression. As secondary outcome, refill adherence was compared using logistic regression. Results From March to July 2015, we enrolled 39 IG and 41 CG patients. At follow-up, CARAT scores did not differ between IG and CG (−0.19; 95% confidence interval [CI], −2.57 to 2.20), neither did patient numbers with ICS adherence >80% (0.82; 95% CI, 0.28–2.37). Among EMI users, CARAT scores did not differ, but ICS adherence >80% showed a 4.52-fold increase (95% CI, 1.56–13.1) compared with EMI nonusers. Conclusion Among community-dwelling asthma patients, pharmacist monitoring did not affect CARAT scores, but EMI use showed improved ICS refill adherence. Springer International Publishing 2017-06-09 2017 /pmc/articles/PMC5541115/ /pubmed/28597176 http://dx.doi.org/10.1007/s11096-017-0495-6 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Research Article
Kuipers, Esther
Wensing, Michel
de Smet, Peter
Teichert, Martina
Self-management research of asthma and good drug use (SMARAGD study): a pilot trial
title Self-management research of asthma and good drug use (SMARAGD study): a pilot trial
title_full Self-management research of asthma and good drug use (SMARAGD study): a pilot trial
title_fullStr Self-management research of asthma and good drug use (SMARAGD study): a pilot trial
title_full_unstemmed Self-management research of asthma and good drug use (SMARAGD study): a pilot trial
title_short Self-management research of asthma and good drug use (SMARAGD study): a pilot trial
title_sort self-management research of asthma and good drug use (smaragd study): a pilot trial
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541115/
https://www.ncbi.nlm.nih.gov/pubmed/28597176
http://dx.doi.org/10.1007/s11096-017-0495-6
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