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PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome
The long non-coding RNA PARTICLE (Gene PARTICL- ‘Promoter of MAT2A-Antisense RadiaTion Induced Circulating LncRNA) partakes in triple helix (triplex) formation, is transiently elevated following low dose irradiation and regulates transcription of its neighbouring gene - Methionine adenosyltransferas...
Autores principales: | O’Leary, Valerie Bríd, Smida, Jan, Buske, Fabian Andreas, Carrascosa, Laura Garcia, Azimzadeh, Omid, Maugg, Doris, Hain, Sarah, Tapio, Soile, Heidenreich, Wolfgang, Kerr, James, Trau, Matt, Ovsepian, Saak Victor, Atkinson, Michael John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541130/ https://www.ncbi.nlm.nih.gov/pubmed/28769061 http://dx.doi.org/10.1038/s41598-017-07295-5 |
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