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Performance and in-house validation of a bioassay for the determination of beta1-autoantibodies found in patients with cardiomyopathy

BACKGROUND: Autoantibodies specific for the adrenergic beta1-receptor were identified to be an essential factor for the pathogenesis of dilated cardiomyopathy. For the detection of these autoantibodies, a bioassay was developed and has been used, measuring the positive chronotropic effect on spontan...

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Detalles Bibliográficos
Autores principales:	Wenzel, Katrin, Schulze-Rothe, Sarah, Haberland, Annekathrin, Müller, Johannes, Wallukat, Gerd, Davideit, Hanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541141/ https://www.ncbi.nlm.nih.gov/pubmed/28795160 http://dx.doi.org/10.1016/j.heliyon.2017.e00362

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