Cell-to-cell heterogeneity of EWSR1-FLI1 activity determines proliferation/migration choices in Ewing sarcoma cells

Ewing sarcoma is characterized by the expression of the chimeric EWSR1-FLI1 transcription factor. Proteomic analyses indicate that the decrease of EWSR1-FLI1 expression leads to major changes in effectors of the dynamics of the actin cytoskeleton and the adhesion processes with a shift from cell-to-...

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Detalles Bibliográficos
Autores principales: Franzetti, G-A, Laud-Duval, K, van der Ent, W, Brisac, A, Irondelle, M, Aubert, S, Dirksen, U, Bouvier, C, de Pinieux, G, Snaar-Jagalska, E, Chavrier, P, Delattre, O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541267/
https://www.ncbi.nlm.nih.gov/pubmed/28135250
http://dx.doi.org/10.1038/onc.2016.498

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