MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target

MUC13 is a transmembrane mucin glycoprotein that is over produced by many cancers, although its functions are not fully understood. Nuclear factor-κB (NF-κB) is a key transcription factor promoting cancer cell survival, but therapeutically targeting this pathway has proved difficult because NF-κB ha...

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Detalles Bibliográficos
Autores principales: Sheng, Y H, He, Y, Hasnain, S Z, Wang, R, Tong, H, Clarke, D T, Lourie, R, Oancea, I, Wong, K Y, Lumley, J W, Florin, T H, Sutton, P, Hooper, J D, McMillan, N A, McGuckin, M A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541270/
https://www.ncbi.nlm.nih.gov/pubmed/27399336
http://dx.doi.org/10.1038/onc.2016.241

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