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SAXS4COLL: an integrated software tool for analysing fibrous collagen-based tissues

This article provides an overview of a new integrated software tool for reduction and analysis of small-angle X-ray scattering (SAXS) data from fibrous collagen tissues, with some wider applicability to other cylindrically symmetric scattering systems. SAXS4COLL combines interactive features for dat...

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Detalles Bibliográficos
Autores principales: Abass, Ahmed, Bell, James S., Spang, Martin T., Hayes, Sally, Meek, Keith M., Boote, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541358/
https://www.ncbi.nlm.nih.gov/pubmed/28808439
http://dx.doi.org/10.1107/S1600576717007877
Descripción
Sumario:This article provides an overview of a new integrated software tool for reduction and analysis of small-angle X-ray scattering (SAXS) data from fibrous collagen tissues, with some wider applicability to other cylindrically symmetric scattering systems. SAXS4COLL combines interactive features for data pre-processing, bespoke background subtraction, semi-automated peak detection and calibration. Both equatorial and meridional SAXS peak parameters can be measured, and the former can be deconstructed into cylinder and lattice contributions. Finally, the software combines functionality for determination of collagen spatial order parameters with a rudimentary orientation plot capability.