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Improved anticancer drug response prediction in cell lines using matrix factorization with similarity regularization

BACKGROUND: Human cancer cell lines are used in research to study the biology of cancer and to test cancer treatments. Recently there are already some large panels of several hundred human cancer cell lines which are characterized with genomic and pharmacological data. The ability to predict drug re...

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Detalles Bibliográficos
Autores principales:	Wang, Lin, Li, Xiaozhong, Zhang, Louxin, Gao, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541434/ https://www.ncbi.nlm.nih.gov/pubmed/28768489 http://dx.doi.org/10.1186/s12885-017-3500-5

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