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Colorectal cancer in a patient with intestinal schistosomiasis: a case report from Kilimanjaro Christian Medical Center Northern Zone Tanzania

BACKGROUND: Colorectal cancer associated with chronic intestinal schistosomiasis has been linked with the chronic inflammation as a result of schistosomal ova deposition in the submucosal layer of the intestine. Among all species Schistosoma japonicum has been more linked to development of colorecta...

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Autores principales: Herman, Ayesiga M, Kishe, Alfred, Babu, Heri, Shilanaiman, Hilary, Tarmohamed, Murad, Lodhia, Jay, Amsi, Patrick, Pyuza, Jeremia, Mremi, Alex, Mwasamwaja, Amos, Nyindo, Mramba, Chilonga, Kondo, Msuya, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541651/
https://www.ncbi.nlm.nih.gov/pubmed/28768520
http://dx.doi.org/10.1186/s12957-017-1217-1
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author Herman, Ayesiga M
Kishe, Alfred
Babu, Heri
Shilanaiman, Hilary
Tarmohamed, Murad
Lodhia, Jay
Amsi, Patrick
Pyuza, Jeremia
Mremi, Alex
Mwasamwaja, Amos
Nyindo, Mramba
Chilonga, Kondo
Msuya, David
author_facet Herman, Ayesiga M
Kishe, Alfred
Babu, Heri
Shilanaiman, Hilary
Tarmohamed, Murad
Lodhia, Jay
Amsi, Patrick
Pyuza, Jeremia
Mremi, Alex
Mwasamwaja, Amos
Nyindo, Mramba
Chilonga, Kondo
Msuya, David
author_sort Herman, Ayesiga M
collection PubMed
description BACKGROUND: Colorectal cancer associated with chronic intestinal schistosomiasis has been linked with the chronic inflammation as a result of schistosomal ova deposition in the submucosal layer of the intestine. Among all species Schistosoma japonicum has been more linked to development of colorectal cancer as compared to Schistosoma mansoni due to absence of population-based studies to support the association. Despite the weak evidence, some cases have been reported associating S. mansoni with development of colorectal cancer. CASE PRESENTATION: We report a patient who presented to us as a case of intestinal obstruction and found to have a constrictive lesion at the sigmoid colon at laparotomy, then later found to have colorectal cancer with deposited S. mansoni ova at histology. CONCLUSION: Given the known late complications of schistosomiasis, and as S. mansoni is endemic in some parts of Tanzania, epidemiological studies are recommended to shed more light on its association with colorectal cancer.
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spelling pubmed-55416512017-08-07 Colorectal cancer in a patient with intestinal schistosomiasis: a case report from Kilimanjaro Christian Medical Center Northern Zone Tanzania Herman, Ayesiga M Kishe, Alfred Babu, Heri Shilanaiman, Hilary Tarmohamed, Murad Lodhia, Jay Amsi, Patrick Pyuza, Jeremia Mremi, Alex Mwasamwaja, Amos Nyindo, Mramba Chilonga, Kondo Msuya, David World J Surg Oncol Case Report BACKGROUND: Colorectal cancer associated with chronic intestinal schistosomiasis has been linked with the chronic inflammation as a result of schistosomal ova deposition in the submucosal layer of the intestine. Among all species Schistosoma japonicum has been more linked to development of colorectal cancer as compared to Schistosoma mansoni due to absence of population-based studies to support the association. Despite the weak evidence, some cases have been reported associating S. mansoni with development of colorectal cancer. CASE PRESENTATION: We report a patient who presented to us as a case of intestinal obstruction and found to have a constrictive lesion at the sigmoid colon at laparotomy, then later found to have colorectal cancer with deposited S. mansoni ova at histology. CONCLUSION: Given the known late complications of schistosomiasis, and as S. mansoni is endemic in some parts of Tanzania, epidemiological studies are recommended to shed more light on its association with colorectal cancer. BioMed Central 2017-08-02 /pmc/articles/PMC5541651/ /pubmed/28768520 http://dx.doi.org/10.1186/s12957-017-1217-1 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Herman, Ayesiga M
Kishe, Alfred
Babu, Heri
Shilanaiman, Hilary
Tarmohamed, Murad
Lodhia, Jay
Amsi, Patrick
Pyuza, Jeremia
Mremi, Alex
Mwasamwaja, Amos
Nyindo, Mramba
Chilonga, Kondo
Msuya, David
Colorectal cancer in a patient with intestinal schistosomiasis: a case report from Kilimanjaro Christian Medical Center Northern Zone Tanzania
title Colorectal cancer in a patient with intestinal schistosomiasis: a case report from Kilimanjaro Christian Medical Center Northern Zone Tanzania
title_full Colorectal cancer in a patient with intestinal schistosomiasis: a case report from Kilimanjaro Christian Medical Center Northern Zone Tanzania
title_fullStr Colorectal cancer in a patient with intestinal schistosomiasis: a case report from Kilimanjaro Christian Medical Center Northern Zone Tanzania
title_full_unstemmed Colorectal cancer in a patient with intestinal schistosomiasis: a case report from Kilimanjaro Christian Medical Center Northern Zone Tanzania
title_short Colorectal cancer in a patient with intestinal schistosomiasis: a case report from Kilimanjaro Christian Medical Center Northern Zone Tanzania
title_sort colorectal cancer in a patient with intestinal schistosomiasis: a case report from kilimanjaro christian medical center northern zone tanzania
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541651/
https://www.ncbi.nlm.nih.gov/pubmed/28768520
http://dx.doi.org/10.1186/s12957-017-1217-1
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