Cargando…
Randomized controlled pilot trial of supportive text messages for patients with depression
BACKGROUND: Depression is projected to be the primary cause of disability worldwide by 2030. In a recent survey, the most commonly cited unmet need among 42.4% of depressed Albertans was the lack of sufficient, accessible, and affordable counselling. Our aim was to test the efficacy of a supportive...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541655/ https://www.ncbi.nlm.nih.gov/pubmed/28768493 http://dx.doi.org/10.1186/s12888-017-1448-2 |
_version_ | 1783254856154218496 |
---|---|
author | Agyapong, Vincent I. O. Juhás, Michal Ohinmaa, Arto Omeje, Joy Mrklas, Kelly Suen, Victoria Y. M. Dursun, Serdar M. Greenshaw, Andrew J. |
author_facet | Agyapong, Vincent I. O. Juhás, Michal Ohinmaa, Arto Omeje, Joy Mrklas, Kelly Suen, Victoria Y. M. Dursun, Serdar M. Greenshaw, Andrew J. |
author_sort | Agyapong, Vincent I. O. |
collection | PubMed |
description | BACKGROUND: Depression is projected to be the primary cause of disability worldwide by 2030. In a recent survey, the most commonly cited unmet need among 42.4% of depressed Albertans was the lack of sufficient, accessible, and affordable counselling. Our aim was to test the efficacy of a supportive text messaging mobile health intervention in improving treatment outcomes in depressed patients. METHODS: We performed a single-rater-blinded randomized trial involving 73 patients with Major Depressive Disorder. Patients in the intervention group (n = 35) received twice-daily supportive text messages for 3 months while those in the control group (n = 38) received a single text message every fortnight thanking them for participating in the study. The primary outcome of this study was: “Mean changes in the BDI scores from baseline“. RESULTS: After adjusting for baseline BDI scores, a significant difference remained in the 3 month mean BDI scores between the intervention and control groups: (20.8 (SD = 11.7) vs. 24.9 (SD = 11.5), F (1, 60) = 4.83, p = 0.03, ηp2 = 0.07). The mean difference in the BDI scores change was significant with an effect size (Cohen’s d) of 0.67. Furthermore, after adjusting for baseline scores, a significant difference remained in the 3 month mean self-rated VAS scores (EQ-5D-5 L scale) between the intervention and control groups, 65.7 (SD = 15.3) vs. 57.4 (SD = 22.9), F (1, 60) =4.16, p = 0.05, ηp2 = 0.065. The mean difference in change mean self-rated VAS scores was also statistically significant with an effect size (Cohen’s d) of 0.51. CONCLUSIONS: Our findings suggest that supportive text messages are a potentially useful psychological intervention for depression, especially in underserved populations. Further studies are needed to explore the implications of our findings in larger clinical samples. TRIAL REGISTRATION: ClinicalTrials.gov NCT02327858. Registered 24 December 2014. |
format | Online Article Text |
id | pubmed-5541655 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-55416552017-08-07 Randomized controlled pilot trial of supportive text messages for patients with depression Agyapong, Vincent I. O. Juhás, Michal Ohinmaa, Arto Omeje, Joy Mrklas, Kelly Suen, Victoria Y. M. Dursun, Serdar M. Greenshaw, Andrew J. BMC Psychiatry Research Article BACKGROUND: Depression is projected to be the primary cause of disability worldwide by 2030. In a recent survey, the most commonly cited unmet need among 42.4% of depressed Albertans was the lack of sufficient, accessible, and affordable counselling. Our aim was to test the efficacy of a supportive text messaging mobile health intervention in improving treatment outcomes in depressed patients. METHODS: We performed a single-rater-blinded randomized trial involving 73 patients with Major Depressive Disorder. Patients in the intervention group (n = 35) received twice-daily supportive text messages for 3 months while those in the control group (n = 38) received a single text message every fortnight thanking them for participating in the study. The primary outcome of this study was: “Mean changes in the BDI scores from baseline“. RESULTS: After adjusting for baseline BDI scores, a significant difference remained in the 3 month mean BDI scores between the intervention and control groups: (20.8 (SD = 11.7) vs. 24.9 (SD = 11.5), F (1, 60) = 4.83, p = 0.03, ηp2 = 0.07). The mean difference in the BDI scores change was significant with an effect size (Cohen’s d) of 0.67. Furthermore, after adjusting for baseline scores, a significant difference remained in the 3 month mean self-rated VAS scores (EQ-5D-5 L scale) between the intervention and control groups, 65.7 (SD = 15.3) vs. 57.4 (SD = 22.9), F (1, 60) =4.16, p = 0.05, ηp2 = 0.065. The mean difference in change mean self-rated VAS scores was also statistically significant with an effect size (Cohen’s d) of 0.51. CONCLUSIONS: Our findings suggest that supportive text messages are a potentially useful psychological intervention for depression, especially in underserved populations. Further studies are needed to explore the implications of our findings in larger clinical samples. TRIAL REGISTRATION: ClinicalTrials.gov NCT02327858. Registered 24 December 2014. BioMed Central 2017-08-02 /pmc/articles/PMC5541655/ /pubmed/28768493 http://dx.doi.org/10.1186/s12888-017-1448-2 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Agyapong, Vincent I. O. Juhás, Michal Ohinmaa, Arto Omeje, Joy Mrklas, Kelly Suen, Victoria Y. M. Dursun, Serdar M. Greenshaw, Andrew J. Randomized controlled pilot trial of supportive text messages for patients with depression |
title | Randomized controlled pilot trial of supportive text messages for patients with depression |
title_full | Randomized controlled pilot trial of supportive text messages for patients with depression |
title_fullStr | Randomized controlled pilot trial of supportive text messages for patients with depression |
title_full_unstemmed | Randomized controlled pilot trial of supportive text messages for patients with depression |
title_short | Randomized controlled pilot trial of supportive text messages for patients with depression |
title_sort | randomized controlled pilot trial of supportive text messages for patients with depression |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541655/ https://www.ncbi.nlm.nih.gov/pubmed/28768493 http://dx.doi.org/10.1186/s12888-017-1448-2 |
work_keys_str_mv | AT agyapongvincentio randomizedcontrolledpilottrialofsupportivetextmessagesforpatientswithdepression AT juhasmichal randomizedcontrolledpilottrialofsupportivetextmessagesforpatientswithdepression AT ohinmaaarto randomizedcontrolledpilottrialofsupportivetextmessagesforpatientswithdepression AT omejejoy randomizedcontrolledpilottrialofsupportivetextmessagesforpatientswithdepression AT mrklaskelly randomizedcontrolledpilottrialofsupportivetextmessagesforpatientswithdepression AT suenvictoriaym randomizedcontrolledpilottrialofsupportivetextmessagesforpatientswithdepression AT dursunserdarm randomizedcontrolledpilottrialofsupportivetextmessagesforpatientswithdepression AT greenshawandrewj randomizedcontrolledpilottrialofsupportivetextmessagesforpatientswithdepression |