Anti-Mullerian hormone is linked to the type of early pregnancy loss in idiopathic recurrent miscarriage: a retrospective cohort study

We correlated Anti-Mullerian hormone (AMH) levels and other parameters for ovarian reserve to the gestational age at the time of pregnancy loss in women with idiopathic recurrent miscarriage. In a retrospective study, 79 patients had suffered a total of 266 miscarriages. When comparing women with an...

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Autores principales: Pils, Sophie, Stepien, Natalia, Kurz, Christine, Nouri, Kazem, Promberger, Regina, Ott, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541661/
https://www.ncbi.nlm.nih.gov/pubmed/28768516
http://dx.doi.org/10.1186/s12958-017-0278-x
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author Pils, Sophie
Stepien, Natalia
Kurz, Christine
Nouri, Kazem
Promberger, Regina
Ott, Johannes
author_facet Pils, Sophie
Stepien, Natalia
Kurz, Christine
Nouri, Kazem
Promberger, Regina
Ott, Johannes
author_sort Pils, Sophie
collection PubMed
description We correlated Anti-Mullerian hormone (AMH) levels and other parameters for ovarian reserve to the gestational age at the time of pregnancy loss in women with idiopathic recurrent miscarriage. In a retrospective study, 79 patients had suffered a total of 266 miscarriages. When comparing women with an “unembryonic” to those with an “embryonic” most recent miscarriage, there was no difference in median age (36.3 years, IQR 31.6–40.1 versus 34.2 years, IQR 29.9–38.0; p = 0.303) but in median AMH levels (0.7, IQR 0.2–18, versus median 1.8, IQR 1.3–3.3, respectively, p = 0.044) and in the rate of patients with an AMH ≤ 1 ng/mL (23/37, 62.2%, versus 8/42, 19%; p < 0.001). Thus, AMH might add to the diagnostic process in recurrent miscarriage in the future.
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spelling pubmed-55416612017-08-07 Anti-Mullerian hormone is linked to the type of early pregnancy loss in idiopathic recurrent miscarriage: a retrospective cohort study Pils, Sophie Stepien, Natalia Kurz, Christine Nouri, Kazem Promberger, Regina Ott, Johannes Reprod Biol Endocrinol Short Communication We correlated Anti-Mullerian hormone (AMH) levels and other parameters for ovarian reserve to the gestational age at the time of pregnancy loss in women with idiopathic recurrent miscarriage. In a retrospective study, 79 patients had suffered a total of 266 miscarriages. When comparing women with an “unembryonic” to those with an “embryonic” most recent miscarriage, there was no difference in median age (36.3 years, IQR 31.6–40.1 versus 34.2 years, IQR 29.9–38.0; p = 0.303) but in median AMH levels (0.7, IQR 0.2–18, versus median 1.8, IQR 1.3–3.3, respectively, p = 0.044) and in the rate of patients with an AMH ≤ 1 ng/mL (23/37, 62.2%, versus 8/42, 19%; p < 0.001). Thus, AMH might add to the diagnostic process in recurrent miscarriage in the future. BioMed Central 2017-08-02 /pmc/articles/PMC5541661/ /pubmed/28768516 http://dx.doi.org/10.1186/s12958-017-0278-x Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Short Communication
Pils, Sophie
Stepien, Natalia
Kurz, Christine
Nouri, Kazem
Promberger, Regina
Ott, Johannes
Anti-Mullerian hormone is linked to the type of early pregnancy loss in idiopathic recurrent miscarriage: a retrospective cohort study
title Anti-Mullerian hormone is linked to the type of early pregnancy loss in idiopathic recurrent miscarriage: a retrospective cohort study
title_full Anti-Mullerian hormone is linked to the type of early pregnancy loss in idiopathic recurrent miscarriage: a retrospective cohort study
title_fullStr Anti-Mullerian hormone is linked to the type of early pregnancy loss in idiopathic recurrent miscarriage: a retrospective cohort study
title_full_unstemmed Anti-Mullerian hormone is linked to the type of early pregnancy loss in idiopathic recurrent miscarriage: a retrospective cohort study
title_short Anti-Mullerian hormone is linked to the type of early pregnancy loss in idiopathic recurrent miscarriage: a retrospective cohort study
title_sort anti-mullerian hormone is linked to the type of early pregnancy loss in idiopathic recurrent miscarriage: a retrospective cohort study
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541661/
https://www.ncbi.nlm.nih.gov/pubmed/28768516
http://dx.doi.org/10.1186/s12958-017-0278-x
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