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An Initial Investigation of an Alternative Model to Study rat Primordial Germ Cell Epigenetic Reprogramming

BACKGROUND: Primordial germ cells (PGC) are the precursors of the gametes. During pre-natal development, PGC undergo an epigenetic reprogramming when bulk DNA demethylation occurs and is followed by sex-specific de novo methylation. The de novo methylation and the maintenance of the methylation patt...

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Detalles Bibliográficos
Autores principales:	Cantão, Isabelle Hernandez, Tesser, Renato Borges, Stumpp, Taiza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541664/ https://www.ncbi.nlm.nih.gov/pubmed/28785173 http://dx.doi.org/10.1186/s12575-017-0058-1

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