Cargando…

SRGN-TGFβ2 regulatory loop confers invasion and metastasis in triple-negative breast cancer

Patients with triple-negative breast cancers (TNBC) are at a high risk for a recurrent or metastatic disease, and the molecular mechanisms associated with this risk are unclear. Proteoglycan serglycin (SRGN) proteins are involved in tumor metastasis, but their role in TNBC has not yet been elucidate...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Z, Deng, Y, Zheng, G, Jia, X, Xiong, Y, Luo, K, Qiu, Q, Qiu, Ni, Yin, J, Lu, M, Liu, H, Gu, Y, He, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541705/
https://www.ncbi.nlm.nih.gov/pubmed/28692037
http://dx.doi.org/10.1038/oncsis.2017.53