Estrogen-like and tissue-selective effects of 7-methoxycoumarin from Ficus umbellata (Moraceae): an in vitro and in vivo study

BACKGROUND: Ficus umbellata is a medicinal plant previously shown to endow estrogenic properties. Its major component was isolated and characterized as 7-methoxycoumarin (MC). Noteworthy, coumarins and the respective active metabolite 7-hydroxycoumarin analogs have shown aromatase inhibitory activit...

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Detalles Bibliográficos
Autores principales: Zingue, Stéphane, Michel, Thomas, Nde, Chantal Beatrice Magne, Njuh, Amstrong Nang, Cisilotto, Julia, Ndinteh, Derek Tantoh, Clyne, Colin, Fernandez, Xavier, Creczynski-Pasa, Tânia Beatriz, Njamen, Dieudonné
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541738/
https://www.ncbi.nlm.nih.gov/pubmed/28768532
http://dx.doi.org/10.1186/s12906-017-1895-9

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