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MBD2 Regulates Th17 Cell Differentiation and Experimental Severe Asthma by Affecting IRF4 Expression

Th17 cells and IL-17 participate in airway neutrophil infiltration characteristics in the pathogenesis of severe asthma. Methyl-CpG binding domain protein 2 (MBD2) expression increased in CD4(+) T cells in peripheral blood samples of asthma patients. However, little is known about that epigenetic re...

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Detalles Bibliográficos
Autores principales:	Jia, Aijun, Wang, Yueling, Sun, Wenjin, Xiao, Bing, Wei, Yan, Qiu, Lulu, Mu, Lin, Xu, Li, Li, Jianmin, Zhang, Xiufeng, Liu, Da, Peng, Cong, Zhang, Dongshan, Xiang, Xudong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541825/ https://www.ncbi.nlm.nih.gov/pubmed/28808358 http://dx.doi.org/10.1155/2017/6249685

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