Cargando…
MBD2 Regulates Th17 Cell Differentiation and Experimental Severe Asthma by Affecting IRF4 Expression
Th17 cells and IL-17 participate in airway neutrophil infiltration characteristics in the pathogenesis of severe asthma. Methyl-CpG binding domain protein 2 (MBD2) expression increased in CD4(+) T cells in peripheral blood samples of asthma patients. However, little is known about that epigenetic re...
Autores principales: | Jia, Aijun, Wang, Yueling, Sun, Wenjin, Xiao, Bing, Wei, Yan, Qiu, Lulu, Mu, Lin, Xu, Li, Li, Jianmin, Zhang, Xiufeng, Liu, Da, Peng, Cong, Zhang, Dongshan, Xiang, Xudong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541825/ https://www.ncbi.nlm.nih.gov/pubmed/28808358 http://dx.doi.org/10.1155/2017/6249685 |
Ejemplares similares
-
MBD2 mediates Th17 cell differentiation by regulating MINK1 in Th17-dominant asthma
por: Chen, Zhifeng, et al.
Publicado: (2022) -
Androgen Plays a Potential Novel Hormonal Therapeutic Role in Th17 Cells Predominant Neutrophilic Severe Asthma by Attenuating BECs Regulated Th17 Cells Differentiation via MBD2 Expression
por: Wasti, Binaya, et al.
Publicado: (2022) -
Bronchial epithelial cells of young and old mice directly regulate the differentiation of Th2 and Th17
por: Liu, Da, et al.
Publicado: (2019) -
MBD2 as a Potential Novel Biomarker for Identifying Severe Asthma With Different Endotypes
por: Chen, Zhifeng, et al.
Publicado: (2021) -
Comparison of the roles of house dust mite allergens, ovalbumin and lipopolysaccharides in the sensitization of mice to establish a model of severe neutrophilic asthma
por: Jia, Aijun, et al.
Publicado: (2017)