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Direct measurement of the strength of microtubule attachment to yeast centrosomes

Centrosomes, or spindle pole bodies (SPBs) in yeast, are vital mechanical hubs that maintain load-bearing attachments to microtubules during mitotic spindle assembly, spindle positioning, and chromosome segregation. However, the strength of microtubule-centrosome attachments is unknown, and the poss...

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Detalles Bibliográficos
Autores principales: Fong, Kimberly K., Sarangapani, Krishna K., Yusko, Erik C., Riffle, Michael, Llauró, Aida, Graczyk, Beth, Davis, Trisha N., Asbury, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541836/
https://www.ncbi.nlm.nih.gov/pubmed/28331072
http://dx.doi.org/10.1091/mbc.E17-01-0034