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Mechanically patterned neuromuscular junctions-in-a-dish have improved functional maturation
Motor neuron (MN) diseases are progressive disorders resulting from degeneration of neuromuscular junctions (NMJs), which form the connection between MNs and muscle fibers. NMJ-in-a-dish models have been developed to examine human MN-associated dysfunction with disease; however such coculture models...
Autores principales: | Happe, Cassandra L., Tenerelli, Kevin P., Gromova, Anastasia K., Kolb, Frederic, Engler, Adam J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541845/ https://www.ncbi.nlm.nih.gov/pubmed/28495800 http://dx.doi.org/10.1091/mbc.E17-01-0046 |
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