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Increased lateral microtubule contact at the cell cortex is sufficient to drive mammalian spindle elongation

The spindle is a dynamic structure that changes its architecture and size in response to biochemical and physical cues. For example, a simple physical change, cell confinement, can trigger centrosome separation and increase spindle steady-state length at metaphase. How this occurs is not understood,...

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Detalles Bibliográficos
Autores principales:	Guild, Joshua, Ginzberg, Miriam B., Hueschen, Christina L., Mitchison, Timothy J., Dumont, Sophie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541847/ https://www.ncbi.nlm.nih.gov/pubmed/28468979 http://dx.doi.org/10.1091/mbc.E17-03-0171

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