Single cell immune profiling by mass cytometry of newly diagnosed chronic phase chronic myeloid leukemia treated with nilotinib

Monitoring of single cell signal transduction in leukemic cellular subsets has been proposed to provide deeper understanding of disease biology and prognosis, but has so far not been tested in a clinical trial of targeted therapy. We developed a complete mass cytometry analysis pipeline for characte...

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Detalles Bibliográficos
Autores principales: Gullaksen, Stein-Erik, Skavland, Jørn, Gavasso, Sonia, Tosevski, Vinko, Warzocha, Krzysztof, Dumrese, Claudia, Ferrant, Augustin, Gedde-Dahl, Tobias, Hellmann, Andrzej, Janssen, Jeroen, Labar, Boris, Lang, Alois, Majeed, Waleed, Mihaylov, Georgi, Stentoft, Jesper, Stenke, Leif, Thaler, Josef, Thielen, Noortje, Verhoef, Gregor, Voglova, Jaroslava, Ossenkoppele, Gert, Hochhaus, Andreas, Hjorth-Hansen, Henrik, Mustjoki, Satu, Sopper, Sieghart, Giles, Francis, Porkka, Kimmo, Wolf, Dominik, Gjertsen, Bjørn Tore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541871/
https://www.ncbi.nlm.nih.gov/pubmed/28522574
http://dx.doi.org/10.3324/haematol.2017.167080

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