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phydms: software for phylogenetic analyses informed by deep mutational scanning
It has recently become possible to experimentally measure the effects of all amino-acid point mutations to proteins using deep mutational scanning. These experimental measurements can inform site-specific phylogenetic substitution models of gene evolution in nature. Here we describe software that ef...
Autores principales: | Hilton, Sarah K., Doud, Michael B., Bloom, Jesse D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541924/ https://www.ncbi.nlm.nih.gov/pubmed/28785526 http://dx.doi.org/10.7717/peerj.3657 |
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