Chemotherapeutic xCT inhibitors sorafenib and erastin unraveled with the synaptic optogenetic function analysis tool

In the search for new potential chemotherapeutics, the compounds’ toxicity to healthy cells is an important factor. The brain with its functional units, the neurons, is especially endangered during the radio- and chemotherapeutic treatment of brain tumors. The effect of the potential compounds not o...

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Detalles Bibliográficos
Autores principales: Dahlmanns, Marc, Yakubov, Eduard, Chen, Daishi, Sehm, Tina, Rauh, Manfred, Savaskan, Nicolai, Wrosch, Jana Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541984/
https://www.ncbi.nlm.nih.gov/pubmed/28835855
http://dx.doi.org/10.1038/cddiscovery.2017.30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541984/
https://www.ncbi.nlm.nih.gov/pubmed/28835855
http://dx.doi.org/10.1038/cddiscovery.2017.30

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